Epigenetic Dysregulation of Trophoblastic Gene Expression in Gestational Trophoblastic Disease

Epigenetic Dysregulation of Trophoblastic Gene Expression in Gestational Trophoblastic Disease

Gestational trophoblastic diseases (GTDs) have not been investigated for their epigenetic marks and consequent transcriptomic changes. Here, we analyzed genome-wide DNA methylation and transcriptome data to reveal the epigenetic basis of disease pathways that may lead to benign or malignant GTDs. RN...

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Bibliographic Details
Main Authors: Zoltan Szabolcsi, Amanda Demeter, Peter Kiraly, Andrea Balogh, Melissa L. Wilson, Jennifer R. King, Szabolcs Hetey, Zsolt Gelencser, Koji Matsuo, Beata Hargitai, Paulette Mhawech-Fauceglia, Petronella Hupuczi, Andras Szilagyi, Zoltan Papp, Lynda D. Roman, Victoria K. Cortessis, Nandor Gabor Than
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomedicines
Subjects:
choriocarcinoma
hydatidiform mole
gestational trophoblastic disease
placental-specific gene
systems biology
trophoblast differentiation
Online Access:https://www.mdpi.com/2227-9059/9/12/1935

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https://www.mdpi.com/2227-9059/9/12/1935

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