The Estrogen Receptor Is Not Essential for All Estrogen Neuroprotection: New Evidence from a New Analog

We synthesized an estrogen analog, ZYC-5, lacking activity at the classical estrogen receptor and examined its neuroprotective potential against necrosis induced by N-methyl-d-aspartate (NMDA) and apoptosis/necrosis induced by the NMDA receptor antagonist (+)-3-(2-carboxypiperazine-4-yl)-propyl-1-ph...

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Bibliographic Details
Main Authors: Shuli Xia, Zu Yun Cai, Liu Lin Thio, Jeong Sook Kim-Han, Laura L. Dugan, Douglas F. Covey, Steven M. Rothman
Format: Article
Language:English
Published: Elsevier 2002-04-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S096999610290478X