Circulating microbial products and acute phase proteins as markers of pathogenesis in lymphatic filarial disease.

Lymphatic filariasis can be associated with development of serious pathology in the form of lymphedema, hydrocele, and elephantiasis in a subset of infected patients. Dysregulated host inflammatory responses leading to systemic immune activation are thought to play a central role in filarial disease...

Full description

Bibliographic Details
Main Authors: R Anuradha, P Jovvian George, N Pavan Kumar, Michael P Fay, V Kumaraswami, Thomas B Nutman, Subash Babu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3369944?pdf=render