The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

Abstract Background E3 ubiquitin ligases play critical roles in regulating cellular signaling pathways by inducing ubiquitylation of key components. RNF111/Arkadia is a RING E3 ubiquitin ligase that activates TGF-β signaling by inducing ubiquitylation and proteasomal degradation of the transcription...

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Bibliographic Details
Main Authors: Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Biology
Subjects:
RNF111
RNF165
TOPORS
UBXN7
RING
Thioredoxin
Online Access:https://doi.org/10.1186/s12915-023-01576-4

Internet

https://doi.org/10.1186/s12915-023-01576-4

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