Cumulative risks of colorectal cancer in Han Chinese patients with Lynch syndrome in Taiwan

Abstract Patients with Lynch syndrome have a high risk of colorectal cancer (CRC). In this study, we estimated the age- and sex-specific cumulative risks of CRC in Han Chinese patients with Lynch syndrome caused by the pathogenic germline mutations in MLH1 or MSH2 in Taiwan. Based on 321 mutation ca...

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Bibliographic Details
Main Authors: Abram Bunya Kamiza, Wen-Chang Wang, Jeng-Fu You, Reiping Tang, Huei-Tzu Chien, Chih-Hsiung Lai, Li-Ling Chiu, Tsai-Ping Lo, Kuan-Yi Hung, Chao A. Hsiung, Chih-Ching Yeh
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88289-2