Baat Gene Knockout Alters Post-Natal Development, the Gut Microbiome, and Reveals Unusual Bile Acids in Mice

Baat Gene Knockout Alters Post-Natal Development, the Gut Microbiome, and Reveals Unusual Bile Acids in Mice

Bile acids (BAs) are steroid detergents in bile that contribute to fat absorption, cell signaling, and microbiome interactions. The final step in their synthesis is amino acid conjugation with either glycine or taurine in the liver by the enzyme bile acid-CoA:amino acid N-acyltransferase (BAAT). Her...

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Bibliographic Details
Main Authors: Kerri A. Neugebauer, Maxwell Okros, Douglas V. Guzior, Jeremiah Feiner, Nicholas J. Chargo, Madison Rzepka, Anthony L. Schilmiller, Sandra O’Reilly, A. Daniel Jones, Victoria E. Watson, James P. Luyendyk, Laura R. McCabe, Robert A. Quinn
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Lipid Research
Subjects:
steroid detergents
microbiome interactions
taurocholic acid
conjugation
bile acid-CoA:amino acid N-acyltransferase
peroxisomal acyltransferases
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227522001304

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http://www.sciencedirect.com/science/article/pii/S0022227522001304

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