ASH2L Aggravates Fibrosis and Inflammation through HIPK2 in High Glucose-Induced Glomerular Mesangial Cells

Diabetic nephropathy (DN) is a leading cause of end-stage renal disease and continues to be a threat to patients with diabetes. Dysfunction of glomerular mesangial cells (GMCs) is the main contributing factor to glomerulosclerosis, which is a pathological feature of DN. The epigenetic factor ASH2L h...

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Bibliographic Details
Main Authors: Wen Zhong, Chen Hong, Yejun Dong, Yuhui Li, Chenxi Xiao, Xinhua Liu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/12/2244