Fabrication and Characterization of Paclitaxel and Resveratrol Loaded Soluplus Polymeric Nanoparticles for Improved BBB Penetration for Glioma Management

Fabrication and Characterization of Paclitaxel and Resveratrol Loaded Soluplus Polymeric Nanoparticles for Improved BBB Penetration for Glioma Management

Gliomas are one of the prominent cancers of the central nervous system with limited therapeutic modalities. The present investigation evaluated the synergistic effect of paclitaxel (PAX) and resveratrol (RESV)-loaded Soluplus polymeric nanoparticles (PNPs) against glioma cell lines along with in viv...

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Bibliographic Details
Main Authors: Talib Hussain, Sathishbabu Paranthaman, Syed Mohd Danish Rizvi, Afrasim Moin, Devegowda Vishakante Gowda, Gehad Muhammed Subaiea, Mukhtar Ansari, Abulrahman Sattam Alanazi
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Polymers
Subjects:
brain cancer
combinational therapy
glioma
nano-biotechnology
polymeric nanoparticles
Online Access:https://www.mdpi.com/2073-4360/13/19/3210

Internet

https://www.mdpi.com/2073-4360/13/19/3210

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