Evaluation of 1p Losses in Primary Carcinomas, Local Recurrences and Peripheral Metastases from Colorectal Cancer Patients

Evaluation of 1p Losses in Primary Carcinomas, Local Recurrences and Peripheral Metastases from Colorectal Cancer Patients

Cytogenetic and molecular genetic analyses of colorectal adenomas and carcinomas have shown that loss of the distal part of chromosome arm 1p is common, particularly in tumors of the left colon. Because the importance of 1p loss in colorectal cancer metastases is unknown, we compared the frequency,...

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Bibliographic Details
Main Authors: Lin Thorstensen, Hanne Qvist, Sverre Heim, Gerrit-Jan Liefers, Jahn M. Nesland, Karl-Erik Giercksky, Ragnhild A. Lothe
Format: Article
Language:English
Published: Elsevier 2000-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
colorectal tumor
liver metastasis
allelic imbalance
1p deletion
smallest region of overlap (SRO)
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558600800421

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http://www.sciencedirect.com/science/article/pii/S1476558600800421

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