Dexmedetomidine improves acute lung injury by activating autophagy in a rat hemorrhagic shock and resuscitation model

Dexmedetomidine improves acute lung injury by activating autophagy in a rat hemorrhagic shock and resuscitation model

Abstract Dexmedetomidine (DEX) can reduce lung injury in a hemorrhagic shock (HS) resuscitation (HSR) model in rats by inhibiting inflammation. Here, we aimed to investigate if these effects of DEX are due to autophagy activation. Therefore, we established HSR rat models and divided them into four g...

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Bibliographic Details
Main Authors: Yifu Lu, Hiroko Shimizu, Ryu Nakamura, Yaqiang Li, Risa Sakamoto, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-31483-1

Internet

https://doi.org/10.1038/s41598-023-31483-1

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