Central Composite Design Implemented Azilsartan Medoxomil Loaded Nanoemulsion to Improve Its Aqueous Solubility and Intestinal Permeability: In Vitro and Ex Vivo Evaluation

Central Composite Design Implemented Azilsartan Medoxomil Loaded Nanoemulsion to Improve Its Aqueous Solubility and Intestinal Permeability: In Vitro and Ex Vivo Evaluation

The present research attempted to design and develop a nanoemulsion formulation of azilsartan medoxomil to improve its aqueous solubility and intestinal permeability. Based on the solubility profile, ethyl oleate, tween 80, and Transcutol P were selected as the oil phase, surfactant, and co-surfacta...

Full description

Bibliographic Details
Main Authors: Girish Kumar, Tarun Virmani, Kamla Pathak, Omkulthom Al Kamaly, Asmaa Saleh
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceuticals
Subjects:
azilsartan medoxomil
nanoemulsion
aqueous solubility
bioavailability
central composite design
optimization
Online Access:https://www.mdpi.com/1424-8247/15/11/1343

Internet

https://www.mdpi.com/1424-8247/15/11/1343

Similar Items