Mechanistic approach for the development of ultrafine oil-water emulsions using monoglyceride and blends of medium and long chain triglycerides: enhancement of the solubility and bioavailability of Perphenazine

A kinetically stable ultra-fine oil-water (o/w) emulsion containing Perphenazine and blends of long and medium chain triglycerides was prepared. The purpose of the ultra-fine emulsion was to increase the oral bioavailability of Perphenazine. The formulations were prepared using a low energy emulsifi...

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Bibliographic Details
Main Authors: Sanjula Baboota, Abdullah Gulam Mustafa, Jasjeet Kaur Sahni, Javed Ali
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2016-11-01
Series:Journal of Excipients and Food Chemicals
Online Access:https://jefc.scholasticahq.com/article/1099-mechanistic-approach-for-the-development-of-ultrafine-oil-water-emulsions-using-monoglyceride-and-blends-of-medium-and-long-chain-triglycerides-enhan