Golgi fragmentation – One of the earliest organelle phenotypes in Alzheimer’s disease neurons

Golgi fragmentation – One of the earliest organelle phenotypes in Alzheimer’s disease neurons

Alzheimer’s disease (AD) is the most common cause of dementia, with no current cure. Consequently, alternative approaches focusing on early pathological events in specific neuronal populations, besides targeting the well-studied amyloid beta (Aβ) accumulations and Tau tangles, are needed. In this st...

Full description

Bibliographic Details
Main Authors: Henriette Haukedal, Giulia I. Corsi, Veerendra P. Gadekar, Nadezhda T. Doncheva, Shekhar Kedia, Noortje de Haan, Abinaya Chandrasekaran, Pia Jensen, Pernille Schiønning, Sarah Vallin, Frederik Ravnkilde Marlet, Anna Poon, Carlota Pires, Fawzi Khoder Agha, Hans H. Wandall, Susanna Cirera, Anja Hviid Simonsen, Troels Tolstrup Nielsen, Jørgen Erik Nielsen, Poul Hyttel, Ravi Muddashetty, Blanca I. Aldana, Jan Gorodkin, Deepak Nair, Morten Meyer, Martin Røssel Larsen, Kristine Freude
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
hiPSC
neurons
Golgi fragmentation
disease modelling
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1120086/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1120086/full

Similar Items