Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells

<p>Abstract</p> <p>Background</p> <p>Endothelin-1 (ET-1) is a potent vasoactive peptide, which induces vasoconstriction and proliferation in vascular smooth muscle cells (VSMCs) through activation of endothelin type A (ET<sub>A</sub>) and type B (ET<sub&g...

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Bibliographic Details
Main Authors: Edvinsson Lars, Chen Qing-wen, Xu Cang-Bao
Format: Article
Language:English
Published: BMC 2009-07-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/10/52