Polygenic risk and incident coronary heart disease in a large multiethnic cohort

Polygenic risk and incident coronary heart disease in a large multiethnic cohort

Objective: Many studies support the notion that polygenic risk scores (PRS) improve risk prediction for coronary heart disease (CHD) beyond conventional risk factors. However, PRS are not yet considered risk-enhancing factor in guidelines. Our objective was to determine the predictive performance of...

Full description

Bibliographic Details
Main Authors: Carlos Iribarren, Meng Lu, Roberto Elosua, Martha Gulati, Nathan D. Wong, Roger S. Blumenthal, Steven Nissen, Jamal S. Rana
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:American Journal of Preventive Cardiology
Subjects:
Polygenic risk score
Coronary heart disease
Clinical utility
Primary prevention
Online Access:http://www.sciencedirect.com/science/article/pii/S2666667724000291

Internet

http://www.sciencedirect.com/science/article/pii/S2666667724000291

Similar Items