Insights into the protective immune response by immunization with full-length recombinant TprK protein: cellular and humoral responses

Abstract Syphilis has resurged in many countries, which has called attention to vaccine development. Based on the immunization-based rabbit model of infection with the Nichols strain, this study explored the protective immune response of a controversial syphilis vaccine candidate, TprK, and found th...

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Bibliographic Details
Main Authors: Dan Liu, Rui Chen, Yong-Jing Wang, Wei Li, Li-Li Liu, Li-Rong Lin, Tian-Ci Yang, Man-Li Tong
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00748-1