Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity

Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity

Cadherin EGF LAG seven-pass G-type receptor (Celsr) proteins 1-3 comprise a subgroup of adhesion GPCRs whose functions range from planar cell polarity (PCP) signaling to axon pathfinding and ciliogenesis. Like its Drosophila ortholog, Flamingo, mammalian Celsr1 is a core component of the PCP pathway...

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Bibliographic Details
Main Authors: Lena P. Basta, Parijat Sil, Rebecca A. Jones, Katherine A. Little, Gabriela Hayward-Lara, Danelle Devenport
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
planar cell polarity
PCP
epidermis
CELSR1
CELSR2
cadherin
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1064907/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.1064907/full

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