From Transcriptomics to Treatment in Inherited Optic Neuropathies

From Transcriptomics to Treatment in Inherited Optic Neuropathies

Inherited optic neuropathies, including Leber Hereditary Optic Neuropathy (LHON) and Dominant Optic Atrophy (DOA), are monogenetic diseases with a final common pathway of mitochondrial dysfunction leading to retinal ganglion cell (RGC) death and ultimately loss of vision. They are, therefore, excell...

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Bibliographic Details
Main Authors: Michael James Gilhooley, Nicholas Owen, Mariya Moosajee, Patrick Yu Wai Man
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Genes
Subjects:
transcriptomics
RNA-seq
neuroprotection
DOA
OPA1
LHON
Online Access:https://www.mdpi.com/2073-4425/12/2/147

Internet

https://www.mdpi.com/2073-4425/12/2/147

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