Zfp296 is a novel, pluripotent-specific reprogramming factor.

Zfp296 is a novel, pluripotent-specific reprogramming factor.

Expression of the four transcription factors Oct4, Sox2, Klf4, and c-Myc (OSKM) is sufficient to reprogram somatic cells into induced pluripotent stem (iPSCs). However, this process is slow and inefficient compared with the fusion of somatic cells with embryonic stem cells (ESCs), indicating that ES...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Gerrit Fischedick, Diana C Klein, Guangming Wu, Daniel Esch, Susanne Höing, Dong Wook Han, Peter Reinhardt, Kerstin Hergarten, Natalia Tapia, Hans R Schöler, Jared L Sterneckert
Format: Artikel
Sprache:English
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC3317644?pdf=render

Online

http://europepmc.org/articles/PMC3317644?pdf=render

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