p53-Mediated Radiosensitization of <sup>177</sup>Lu-DOTATATE in Neuroblastoma Tumor Spheroids

p53 is involved in DNA damage response and is an exciting target for radiosensitization in cancer. Targeted radionuclide therapy against somatostatin receptors with <sup>177</sup>Lu-DOTATATE is currently being explored as a treatment for neuroblastoma. The aim of this study was to invest...

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Bibliographic Details
Main Authors: Sara Lundsten, Hanna Berglund, Preeti Jha, Cecilia Krona, Mehran Hariri, Sven Nelander, David P. Lane, Marika Nestor
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/11/1695