Reconstitution of bone-like matrix in osteogenically differentiated mesenchymal stem cell–collagen constructs: A three-dimensional in vitro model to study hematopoietic stem cell niche

Mesenchymal stem/stromal cells (MSCs) and osteoblasts are important niche cells for hematopoietic stem cells (HSCs) in bone marrow osteoblastic niche. Here, we aim to partially reconstitute the bone marrow HSC niche in vitro using collagen microencapsulation for investigation of the interactions bet...

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Bibliographic Details
Main Authors: WY Lai, YY Li, SK Mak, FC Ho, ST Chow, WH Chooi, CH Chow, AY Leung, BP Chan
Format: Article
Language:English
Published: SAGE Publishing 2013-10-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731413508668