In vivo validation of psilacetin as a prodrug yielding modestly lower peripheral psilocin exposure than psilocybin

IntroductionThe use of the psychedelic compound psilocybin in conjunction with psychotherapy has shown promising results in the treatment of psychiatric disorders, though the underlying mechanisms supporting these effects remain unclear. Psilocybin is a Schedule I substance that is dephosphorylated...

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Bibliographic Details
Main Authors: Nathan T. Jones, Laura Wagner, Molly C. Pellitteri Hahn, Cameron O. Scarlett, Cody J. Wenthur
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1303365/full