Alpha- and Beta-Cyclodextrin Inclusion Complexes with 5-Fluorouracil: Characterization and Cytotoxic Activity Evaluation

Alpha- and Beta-Cyclodextrin Inclusion Complexes with 5-Fluorouracil: Characterization and Cytotoxic Activity Evaluation

Cyclodextrins are natural macrocyclic oligosaccharides able to form inclusion complexes with a wide variety of guests, affecting their physicochemical and pharmaceutical properties. In order to obtain an improvement of the bioavailability and solubility of 5-fluorouracil, a pyrimidine analogue used...

Full description

Bibliographic Details
Main Authors: Cristina Di Donato, Margherita Lavorgna, Roberto Fattorusso, Carla Isernia, Marina Isidori, Gaetano Malgieri, Concetta Piscitelli, Chiara Russo, Luigi Russo, Rosa Iacovino
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:Molecules
Subjects:
cyclodextrin
5-fluorouracil
inclusion complex
cytotoxicity
Online Access:http://www.mdpi.com/1420-3049/21/12/1644

Internet

http://www.mdpi.com/1420-3049/21/12/1644

Similar Items