Urokinase-Type Plasminogen Activator Receptor (uPAR) in Inflammation and Disease: A Unique Inflammatory Pathway Activator

Urokinase-Type Plasminogen Activator Receptor (uPAR) in Inflammation and Disease: A Unique Inflammatory Pathway Activator

The urokinase-type plasminogen activator receptor (uPAR) is a unique protease binding receptor, now recognized as a key regulator of inflammation. Initially, uPA/uPAR was considered thrombolytic (clot-dissolving); however, recent studies have demonstrated its predominant immunomodulatory functions i...

Full description

Bibliographic Details
Main Authors: Mostafa Hamada, Kyle Steven Varkoly, Omer Riyadh, Roxana Beladi, Ganesh Munuswamy-Ramanujam, Alan Rawls, Jeanne Wilson-Rawls, Hao Chen, Grant McFadden, Alexandra R. Lucas
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Biomedicines
Subjects:
urokinase-type plasminogen receptor
uPAR
inflammation
cancer
sepsis
virus
Online Access:https://www.mdpi.com/2227-9059/12/6/1167

Internet

https://www.mdpi.com/2227-9059/12/6/1167

Similar Items