Brusatol inhibits the invasion and migration of pancreatic cancer cells by suppressing the NRF2/NF-κB/STAT3 signal cascade

Brusatol inhibits the invasion and migration of pancreatic cancer cells by suppressing the NRF2/NF-κB/STAT3 signal cascade

The previous study has established that brusatol exhibits growth inhibitory and pro-apoptotic effects. However, whether brusatol can suppress the invasion and migration of pancreatic cancer cells remains unclear. Information in The Cancer Genome Atlas database indicates that NRF2 expression is tight...

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Bibliographic Details
Main Authors: Yukai Xiang, Shengjie Dai, Ding Li, Xiandong Zhu, Jiadong Su, Bicheng Chen, Minmin Wu
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Journal of Functional Foods
Subjects:
Pancreatic cancer
Cancer invasion and migration
NRF2/NF-κB/STAT3 pathway
Chemotherapeutic resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622000949

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http://www.sciencedirect.com/science/article/pii/S1756464622000949

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