Neuronal nitric oxide synthase required for erythropoietin modulation of heart function in mice

Neuronal nitric oxide synthase required for erythropoietin modulation of heart function in mice

Introduction: Erythropoietin (EPO) acts primarily in regulating red blood cell production mediated by high EPO receptor (EPOR) expression in erythroid progenitor cells. EPO activity in non-erythroid tissue is evident in mice with EPOR restricted to erythroid tissues (ΔEPORE) that become obese, gluco...

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Bibliographic Details
Main Authors: Jeeyoung Lee, Heather M. Rogers, Danielle A. Springer, Constance T. Noguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Physiology
Subjects:
erythropoietin
neuronal nitric oxide synthase
heart function
heart failure-associated genes
nNOS-knockout mice
hematocrit
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1338476/full

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https://www.frontiersin.org/articles/10.3389/fphys.2024.1338476/full

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