Chimeric antigen receptor T-cell therapy for multiple myeloma

Multiple myeloma (MM) is a malignant plasma cell disorder that remains incurable for most patients, as persistent clonal evolution drives new mutations which confer MM high-risk signatures and resistance to standard care. The past two decades have significantly refashioned the therapeutic options fo...

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Bibliographic Details
Main Authors: Zehua Wang, Chen Chen, Lei Wang, Yongxu Jia, Yanru Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1050522/full