Dynamics of the cellular metabolome during human cytomegalovirus infection.

Viral replication requires energy and macromolecular precursors derived from the metabolic network of the host cell. Despite this reliance, the effect of viral infection on host cell metabolic composition remains poorly understood. Here we applied liquid chromatography-tandem mass spectrometry to me...

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Bibliographic Details
Main Authors: Joshua Munger, Sunil U Bajad, Hilary A Coller, Thomas Shenk, Joshua D Rabinowitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1698944?pdf=render