Weekly intra-amniotic IGF-1 treatment increases growth of growth-restricted ovine fetuses and up-regulates placental amino acid transporters.

Weekly intra-amniotic IGF-1 treatment increases growth of growth-restricted ovine fetuses and up-regulates placental amino acid transporters.

Frequent treatment of the growth-restricted (IUGR) ovine fetus with intra-amniotic IGF-1 increases fetal growth. We aimed to determine whether increased growth was maintained with an extended dosing interval and to examine possible mechanisms. Pregnant ewes were allocated to three groups: Control, a...

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Bibliographic Details
Main Authors: Jibran A Wali, Hendrina A de Boo, José G B Derraik, Hui Hui Phua, Mark H Oliver, Frank H Bloomfield, Jane E Harding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22629469/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22629469/?tool=EBI

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