Evidence for an Intrathecal Immunoglobulin Synthesis by Kappa Free Light Chains in Neurological Patients with an Isolated Band in Isoelectric Focusing

Evidence for an Intrathecal Immunoglobulin Synthesis by Kappa Free Light Chains in Neurological Patients with an Isolated Band in Isoelectric Focusing

The gold standard for detecting intrathecal immunoglobulin synthesis is the determination of the oligoclonal band (OCB) in the cerebrospinal fluid (CSF) using isoelectric focusing (IEF). Controversy still exists regarding the significance of an isolated band in the CSF. A highly promising alternativ...

Full description

Bibliographic Details
Main Authors: Bastian Weiss, Alexander Pichler, Anna Damulina, Arabella Buchmann, Sonja Hochmeister, Thomas Seifert-Held, Christian Enzinger, Juan-Jose Archelos, Michael Khalil
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
immunoglobulin kappa-chains
isoelectric focusing
neuroinflammatory diseases
multiple sclerosis
human
biomarker
Online Access:https://www.mdpi.com/2227-9059/10/9/2202

Internet

https://www.mdpi.com/2227-9059/10/9/2202

Similar Items