Prevention of arthritis by locally synthesized recombinant antibody neutralizing complement component C5.

Treatment of patients suffering from chronic diseases such as rheumatoid arthritis with recombinant antibodies is time consuming and fairly expensive and can be associated with side effects due to generalized depletion of the target molecule. We have addressed these issues by developing an alternati...

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Bibliographic Details
Main Authors: Paolo Durigutto, Paolo Macor, Federica Ziller, Luca De Maso, Fabio Fischetti, Roberto Marzari, Daniele Sblattero, Francesco Tedesco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3591401?pdf=render