Feature-by-feature--evaluating de novo sequence assembly.

The whole-genome sequence assembly (WGSA) problem is among one of the most studied problems in computational biology. Despite the availability of a plethora of tools (i.e., assemblers), all claiming to have solved the WGSA problem, little has been done to systematically compare their accuracy and po...

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Bibliographic Details
Main Authors: Francesco Vezzi, Giuseppe Narzisi, Bud Mishra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3272011?pdf=render