Enhanced Seroconversion to West Nile Virus Proteins in Mice by West Nile Kunjin Replicon Virus-like Particles Expressing Glycoproteins from Crimean–Congo Hemorrhagic Fever Virus

Removal of genes coding for major parts of capsid (C), premembrane (prM), and envelope (E) proteins on the flavivirus genome aborts the production of infectious virus particles where the remaining genome forms a replicon that retains replicability in host cells. The C-prM-E proteins can also be expr...

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Bibliographic Details
Main Authors: Pham-Tue-Hung Tran, Urban Höglund, Olivia Larsson, Sofia Appelberg, Ali Mirazimi, Magnus Johansson, Wessam Melik
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/11/2/233