Development of an Environment-Friendly and Electrochemical Method for the Synthesis of an Oxadiazole Drug-Scaffold That Targets Poly(ADP-Ribose)Polymerase in Human Breast Cancer Cells

Development of an Environment-Friendly and Electrochemical Method for the Synthesis of an Oxadiazole Drug-Scaffold That Targets Poly(ADP-Ribose)Polymerase in Human Breast Cancer Cells

The development of environment-friendly new Poly-adenosine diphosphate (ADP)-ribose Polymerase (PARP) inhibitors are highly essential because of their involvement in the survival of cancer cells. Therefore, a library of indazolyl-substituted-1,3,4-oxadiazoles known to inhibit PARP in cancer cells wa...

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Bibliographic Details
Main Authors: Sindhu M. Parameshwaraiah, Zhang Xi, Akshay Ravish, Arunkumar Mohan, Vanishree Shankarnaik, Dukanya Dukanya, Shreeja Basappa, Habbanakuppe D. Preetham, Ganga Periyasamy, Santhosh L. Gaonkar, Peter E. Lobie, Vijay Pandey, Basappa Basappa
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Catalysts
Subjects:
1,3,4-oxadiazoles
poly(ADP-ribose) polymerase
human breast cancer
auto dock
density function theory
Online Access:https://www.mdpi.com/2073-4344/13/8/1185

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https://www.mdpi.com/2073-4344/13/8/1185

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