Predicting cancer prognosis and drug response from the tumor microbiome

Abstract Tumor gene expression is predictive of patient prognosis in some cancers. However, RNA-seq and whole genome sequencing data contain not only reads from host tumor and normal tissue, but also reads from the tumor microbiome, which can be used to infer the microbial abundances in each tumor....

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Bibliographic Details
Main Authors: Leandro C. Hermida, E. Michael Gertz, Eytan Ruppin
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30512-3