DNA Repair Pathway Alterations in Bladder Cancer
Most bladder tumors have complex genomes characterized by a high mutation burden as well as frequent copy number alterations and chromosomal rearrangements. Alterations in DNA repair pathways—including the double-strand break (DSB) and nucleotide excision repair (NER) pathways—are present in bladder...
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Format: | Article |
Language: | English |
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MDPI AG
2017-03-01
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Series: | Cancers |
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Online Access: | http://www.mdpi.com/2072-6694/9/4/28 |