DNA Repair Pathway Alterations in Bladder Cancer

Most bladder tumors have complex genomes characterized by a high mutation burden as well as frequent copy number alterations and chromosomal rearrangements. Alterations in DNA repair pathways—including the double-strand break (DSB) and nucleotide excision repair (NER) pathways—are present in bladder...

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Bibliographic Details
Main Author: Kent W. Mouw
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/9/4/28