Polymorphisms of Satellite DNA CYP19 Gene and its Association with Increased Risk of Breast Cancer in Isfahan, Iran

Background: Aromatase is a key enzyme in the synthesis of estrogen. This enzyme is encoded by the cytochrome P-450 (CYP19) gene. Overexposure of cells to estrogen causes breast carcinoma and breast cancer patients show a higher level of aromatase expression. The purpose of this study was to investig...

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Bibliographic Details
Main Authors: Seyed Morteza Javadirad, Simin Hemati, Manochehr Tavassoli
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2012-03-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/1049