Analysis of tumor microenvironment composition in vestibular schwannomas: insights into NF2-associated and sporadic variations and their clinical correlations

Analysis of tumor microenvironment composition in vestibular schwannomas: insights into NF2-associated and sporadic variations and their clinical correlations

ObjectiveVestibular schwannomas (VS), benign tumors stemming from the eighth cranial nerve’s Schwann cells, are associated with Merlin gene mutations, inflammation, and the tumor microenvironment (TME), influencing tumor initiation, maintenance, and potential neural dysfunction. Understanding TME co...

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Bibliographic Details
Main Authors: Vera Nickl, David Ziebolz, Charlotte Rumpel, Dennis Klein, Robert Nickl, Eva Rampeltshammer, Camelia M. Monoranu, Ralf-Ingo Ernestus, Cordula Matthies, Mario Löhr, Carsten Hagemann, Maria Breun
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Oncology
Subjects:
vestibular schwannoma
tumor microenvironment
repair cells
immune cells
neurofibromatosis type 2
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1340184/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1340184/full

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