Identification of targets of CD8⁺ T cell responses to malaria liver stages by genome-wide epitope profiling.

CD8⁺ T cells mediate immunity against Plasmodium liver stages. However, the paucity of parasite-specific epitopes of CD8⁺ T cells has limited our current understanding of the mechanisms influencing the generation, maintenance and efficiency of these responses. To identify antigenic epitopes in a str...

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Detalhes bibliográficos
Principais autores: Julius Clemence R Hafalla, Karolis Bauza, Johannes Friesen, Gloria Gonzalez-Aseguinolaza, Adrian V S Hill, Kai Matuschewski
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2013-05-01
coleção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC3649980?pdf=render