Maternal Supplementation with N-Acetylcysteine Modulates the Microbiota-Gut-Brain Axis in Offspring of the Poly I:C Rat Model of Schizophrenia

Maternal Supplementation with N-Acetylcysteine Modulates the Microbiota-Gut-Brain Axis in Offspring of the Poly I:C Rat Model of Schizophrenia

The microbiota-gut-brain axis is a complex interconnected system altered in schizophrenia. The antioxidant N-acetylcysteine (NAC) has been proposed as an adjunctive therapy to antipsychotics in clinical trials, but its role in the microbiota-gut-brain axis has not been sufficiently explored. We aime...

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Bibliographic Details
Main Authors: Diego Romero-Miguel, Marta Casquero-Veiga, Javier Fernández, Nicolás Lamanna-Rama, Vanessa Gómez-Rangel, Carlos Gálvez-Robleño, Cristina Santa-Marta, Claudio J. Villar, Felipe Lombó, Raquel Abalo, Manuel Desco, María Luisa Soto-Montenegro
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Antioxidants
Subjects:
Poly I:C
schizophrenia
microbiota-gut-brain axis
inflammation
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/12/4/970

Internet

https://www.mdpi.com/2076-3921/12/4/970

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