D-4F, an apoA-1 mimetic, decreases airway hyperresponsiveness, inflammation, and oxidative stress in a murine model of asthma[S]

Asthma is characterized by oxidative stress and inflammation of the airways. Although proinflammatory lipids are involved in asthma, therapies targeting them remain lacking. Ac-DW F KA F YDKVAEK F KEA F NH2 (4F) is an apolipoprotein (apo)A-I mimetic that has been shown to preferentially bind oxidize...

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Bibliographic Details
Main Authors: S.D. Nandedkar, D. Weihrauch, H. Xu, Y. Shi, T. Feroah, W. Hutchins, D.A. Rickaby, N. Duzgunes, C.A. Hillery, K.S. Konduri, Jr.K.A. Pritchard
Format: Article
Language:English
Published: Elsevier 2011-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520409307