Intrauterine exposure to 2,3′,4,4′,5-pentachlorobiphenyl alters spermatogenesis and testicular DNA methylation levels in F1 male mice

Intrauterine exposure to 2,3′,4,4′,5-pentachlorobiphenyl alters spermatogenesis and testicular DNA methylation levels in F1 male mice

Polychlorinated biphenyls (PCBs) are synthetic biphenyl compounds with high toxicity. There are a total of 209 homologs, among which 2,3’,4,4’,5-pentachlorobiphenyl (PCB118) is one of the dioxin-like PCBs. PCB118 can accumulate in pregnant mice, leading to fetus directly exposure during development....

Full description

Bibliographic Details
Main Authors: Yu-Rong Tao, Yong-Tao Zhang, Xiao-Ying Han, Lin Zhang, Li-Gang Jiang, Ying Ma, Ling-Jiao Meng, Qi-Long He, Shu-Zhen Liu
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PCB118
Testis
Spermatogonia
Male reproductive toxicity
DNA methylation
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321007648

Internet

http://www.sciencedirect.com/science/article/pii/S0147651321007648

Similar Items