The novel molecular mechanism of pulmonary fibrosis: insight into lipid metabolism from reanalysis of single-cell RNA-seq databases

The novel molecular mechanism of pulmonary fibrosis: insight into lipid metabolism from reanalysis of single-cell RNA-seq databases

Abstract Pulmonary fibrosis (PF) is a severe pulmonary disease with limited available therapeutic choices. Recent evidence increasingly points to abnormal lipid metabolism as a critical factor in PF pathogenesis. Our latest research identifies the dysregulation of low-density lipoprotein (LDL) is a...

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Bibliographic Details
Main Authors: Xiangguang Shi, Yahui Chen, Mengkun Shi, Fei Gao, Lihao Huang, Wei Wang, Dong Wei, Chenyi Shi, Yuexin Yu, Xueyi Xia, Nana Song, Xiaofeng Chen, Jörg H. W. Distler, Chenqi Lu, Jingyu Chen, Jiucun Wang
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Lipids in Health and Disease
Subjects:
Pulmonary fibrosis
Lipid metabolism
Lipid metabolomic gene, Single-cell RNA-sequencing reanalysis
Online Access:https://doi.org/10.1186/s12944-024-02062-8

Internet

https://doi.org/10.1186/s12944-024-02062-8

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