Neural protein synthesis during aging: effects on plasticity and memory

During aging, many experience a decline in cognitive function that includes memory loss. The encoding of long-term memories depends on new protein synthesis, and this is also reduced during aging. Thus, it is possible that changes in the regulation of protein synthesis contribute to the memory impai...

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Bibliographic Details
Main Authors: Lesley A Schimanski, Carol A Barnes
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2010.00026/full