Fangchinoline, a Bisbenzylisoquinoline Alkaloid can Modulate Cytokine-Impelled Apoptosis via the Dual Regulation of NF-κB and AP-1 Pathways

Fangchinoline, a Bisbenzylisoquinoline Alkaloid can Modulate Cytokine-Impelled Apoptosis via the Dual Regulation of NF-κB and AP-1 Pathways

Fangchinoline (FCN) derived from Stephaniae tetrandrine S. Moore can be employed to treat fever, inflammation, rheumatism arthralgia, edema, dysuria, athlete’s foot, and swollen wet sores. FCN can exhibit a plethora of anti-neoplastic effects although its precise mode of action still remai...

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Bibliographic Details
Main Authors: Young Yun Jung, Muthu K. Shanmugam, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Omar H.M. Shair, Jae-Young Um, Gautam Sethi, Kwang Seok Ahn
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Molecules
Subjects:
fangchinoline
NF-κB
AP-1
cancer
apoptosis
Online Access:https://www.mdpi.com/1420-3049/24/17/3127

Internet

https://www.mdpi.com/1420-3049/24/17/3127

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