Neurogenin 2 Converts Mesenchymal Stem Cells into a Neural Precursor Fate and Improves Functional Recovery after Experimental Stroke

Neurogenin 2 Converts Mesenchymal Stem Cells into a Neural Precursor Fate and Improves Functional Recovery after Experimental Stroke

Background: Neurogenin2 (Ngn2) is a proneural gene that directs neuronal differentiation of progenitor cells during development. Here, we investigated whether Ngn2 can reprogram MSCs to adopt a neural precursor fate and enhance the therapeutic effects of MSCs after experimental stroke. Methods: In v...

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Bibliographic Details
Main Authors: Feng Cheng, Xiao Cheng Lu, Huai Yong Hao, Xue Liang Dai, Teng Da Qian, Bao Sheng Huang, Lin Jun Tang, Wan Yu, Li Xin Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Stroke
Mesenchymal stem cells
Neurogenin 2
Cell transplantation
Online Access:http://www.karger.com/Article/FullText/358657

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http://www.karger.com/Article/FullText/358657

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