Association of L-type amino acid transporter 1 (LAT1) with the immune system and prognosis in invasive breast cancer

Abstract L-type amino acid transporter 1 (LAT1), also referred to as SLC7A5, is believed to regulate tumor metabolism and be associated with tumor proliferation. In invasive breast cancer, we clinicopathologically investigated the utility of LAT1 expression. LAT1 expression was evaluated via immunoh...

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Bibliographic Details
Main Authors: Sasagu Kurozumi, Kyoichi Kaira, Hiroshi Matsumoto, Masafumi Kurosumi, Takehiko Yokobori, Yoshikatsu Kanai, Chikako Sekine, Chikako Honda, Ayaka Katayama, Mio Furuya, Sho Shiino, Takaya Makiguchi, Nigel P. Mongan, Emad A. Rakha, Tetsunari Oyama, Takaaki Fujii, Ken Shirabe, Jun Horiguchi
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-06615-8