β-Sitosterol Loaded Nanostructured Lipid Carrier: Physical and Oxidative Stability, In Vitro Simulated Digestion and Hypocholesterolemic Activity

β-Sitosterol Loaded Nanostructured Lipid Carrier: Physical and Oxidative Stability, In Vitro Simulated Digestion and Hypocholesterolemic Activity

The objective of the present study was to explore the potential of nanostructured lipid carriers (NLCs) for improving the oral delivery of β-sitosterol, a poorly water-soluble bioactive component with hypocholesterolemic activity. Two β-sitosterol formulations with different solid lipid compositions...

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Bibliographic Details
Main Authors: Yasamin Soleimanian, Sayed Amir Hossein Goli, Jaleh Varshosaz, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Marzia Cirri, Francesca Maestrelli
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
β-sitosterol
nanostructured lipid carrier
hypocholesterolemic activity
digestion
bioaccessibility
in vitro release
Online Access:https://www.mdpi.com/1999-4923/12/4/386

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https://www.mdpi.com/1999-4923/12/4/386

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