Human RTEL1 Interacts with KPNB1 (Importin β) and NUP153 and Connects Nuclear Import to Nuclear Envelope Stability in S-Phase

Human RTEL1 Interacts with KPNB1 (Importin β) and NUP153 and Connects Nuclear Import to Nuclear Envelope Stability in S-Phase

Regulator of TElomere Length Helicase 1 (RTEL1) is a helicase required for telomere maintenance and genome replication and repair. RTEL1 has been previously shown to participate in the nuclear export of small nuclear RNAs. Here we show that RTEL1 deficiency leads to a nuclear envelope destabilizatio...

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Bibliographic Details
Main Authors: Michael Schertzer, Laurent Jullien, André L. Pinto, Rodrigo T. Calado, Patrick Revy, Arturo Londoño-Vallejo
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
Regulator of TElomere Length Helicase 1
protein import
nuclear envelope
nuclear pore
KPNB1 (importin β)
NUP153
Online Access:https://www.mdpi.com/2073-4409/12/24/2798

Internet

https://www.mdpi.com/2073-4409/12/24/2798

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