Timing constraints of in vivo gag mutations during primary HIV-1 subtype C infection.

Aiming to answer the broad question "When does mutation occur?" this study examined the time of appearance, dominance, and completeness of in vivo Gag mutations in primary HIV-1 subtype C infection.A primary HIV-1C infection cohort comprised of 8 acutely and 34 recently infected subjects w...

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Bibliographic Details
Main Authors: Vladimir Novitsky, Rui Wang, Lauren Margolin, Jeannie Baca, Lemme Kebaabetswe, Raabya Rossenkhan, Caitlin Bonney, Michaela Herzig, David Nkwe, Sikhulile Moyo, Rosemary Musonda, Elias Woldegabriel, Erik van Widenfelt, Joseph Makhema, Stephen Lagakos, M Essex
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2768328?pdf=render